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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP7
All Species:
31.52
Human Site:
S963
Identified Species:
49.52
UniProt:
Q93009
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93009
NP_003461.2
1102
128302
S963
D
E
L
L
E
C
L
S
P
A
T
S
R
T
F
Chimpanzee
Pan troglodytes
XP_510806
1102
128297
S963
D
E
L
L
E
C
L
S
P
A
T
S
R
T
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536979
1086
126326
S947
D
E
L
L
E
C
L
S
P
A
T
S
R
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4J8
1103
128457
S964
D
E
L
L
E
C
L
S
P
A
T
S
R
T
F
Rat
Rattus norvegicus
Q4VSI4
1103
128413
S964
D
E
L
L
E
C
L
S
P
A
T
S
R
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506396
1145
132881
S1006
D
E
L
L
E
C
L
S
P
A
T
S
R
T
F
Chicken
Gallus gallus
Q6U7I1
1101
128279
S963
D
E
L
L
E
C
L
S
P
A
T
S
R
T
F
Frog
Xenopus laevis
NP_001121282
534
61718
R425
Q
N
I
K
I
N
D
R
F
E
F
P
E
Q
L
Zebra Danio
Brachydanio rerio
XP_691215
1103
128646
S964
D
E
L
L
E
C
L
S
P
A
A
S
R
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYQ8
1129
130428
A995
S
N
E
S
I
T
T
A
Q
G
A
Q
K
T
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q7JKC3
1135
131579
V999
Q
R
T
M
Y
K
L
V
S
S
Q
A
L
H
C
Sea Urchin
Strong. purpuratus
XP_780569
1189
136707
A1056
D
T
P
I
E
N
L
A
L
Q
G
T
K
M
Y
Poplar Tree
Populus trichocarpa
XP_002316470
1116
130731
I970
H
N
E
K
I
E
N
I
N
D
Q
Y
W
T
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WU2
1115
130630
N971
T
E
R
I
E
N
I
N
D
Q
Y
W
T
L
R
Baker's Yeast
Sacchar. cerevisiae
P50101
1230
143545
A1004
Q
C
F
E
F
E
V
A
N
D
Y
T
E
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.7
N.A.
99
99
N.A.
92.4
95.9
46
94
N.A.
48.5
N.A.
34.4
54.5
Protein Similarity:
100
99.9
N.A.
98
N.A.
99.7
99.8
N.A.
94.7
97.9
47.4
96.8
N.A.
67.5
N.A.
52.5
69.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
93.3
N.A.
13.3
N.A.
6.6
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
6.6
93.3
N.A.
26.6
N.A.
26.6
53.3
Percent
Protein Identity:
36.9
N.A.
N.A.
36.5
29.4
N.A.
Protein Similarity:
54.3
N.A.
N.A.
54.7
47.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
20
0
54
14
7
0
0
0
% A
% Cys:
0
7
0
0
0
54
0
0
0
0
0
0
0
0
7
% C
% Asp:
60
0
0
0
0
0
7
0
7
14
0
0
0
0
0
% D
% Glu:
0
60
14
7
67
14
0
0
0
7
0
0
14
0
0
% E
% Phe:
0
0
7
0
7
0
0
0
7
0
7
0
0
0
60
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
7
14
20
0
7
7
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
14
0
7
0
0
0
0
0
0
14
0
0
% K
% Leu:
0
0
54
54
0
0
67
0
7
0
0
0
7
7
14
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
0
20
0
0
0
20
7
7
14
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
54
0
0
7
0
0
0
% P
% Gln:
20
0
0
0
0
0
0
0
7
14
14
7
0
7
7
% Q
% Arg:
0
7
7
0
0
0
0
7
0
0
0
0
54
0
7
% R
% Ser:
7
0
0
7
0
0
0
54
7
7
0
54
0
7
0
% S
% Thr:
7
7
7
0
0
7
7
0
0
0
47
14
7
67
0
% T
% Val:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
7
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
14
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _